Home » Biochemistry 12 » Biochemistry Notes for Class 12 Topic “Carbohydrate Metabolism – Diabetes Mellitus” Complete Notes for Class 12

Diabetes Mellitus

Diabetes mellitus (often referred to simply as diabetes) is a group of metabolic diseases characterized by high blood glucose levels. The term comes from two Greek words: “diabetes” comes from a verb that means “to pass through” and refers to the frequent, copious urination that is a characteristic of the disease; the word “meli” is Greek for “honey” so the term “mellitus” refers to the presence of high levels of glucose (sugar) in the blood. In addition to urination, other classic symptoms of diabetes are increased thirst and hunger. The diabetic’s blood contains more glucose than can be taken up by the cells so this excess glusose is therefore released in the urine (a diagnostic characteristic of diabetes is sugar in the urine). The presence of sugar results in more water being drawn into the urine to balance the osmotic pressure, leading to copious urination.

Questions

1. In glycolysis pathway glucose is aerobically converted to ……………… and anaerobically ………………

2. All the reaction steps take place in ………………

3. Glycolysis is the only source of energy in ……………… cells

4. Number of ATPs gained per glucose molecule in Aerobic conditions of glycolysis is ………………

5. Number of ATPs gained per glucose molecule in Anaerobic conditions of glycolysis is ………………

6. Krebs Cycle yield ……………… ATP per mole Glucose

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